Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803860 | 0.84 | BACE1 (0.36) | BACE1SLC6A2SLC6A4 | |
| SCHEMBL6942401 | 0.82 | BACE1 (0.34) | BACE1 | |
| SCHEMBL7804436 | 0.78 | MAPK14 (0.35) | BACE1 | |
| SCHEMBL6942499 | 0.75 | BACE1 (0.34) | BACE1 | |
| SCHEMBL7894895 | 0.70 | BACE1 (0.34) | BACE1 | |
| SCHEMBL7797782 | 0.70 | GRM5 (0.41) | CHRM3GRM5AR | |
| SCHEMBL7805235 | 0.65 | BACE1 (0.32) | BACE1 | |
| SCHEMBL8872284 | 0.64 | HCAR3 (0.42) | — | |
| SCHEMBL7808783 | 0.63 | BACE1 (0.39) | BACE1 | |
| SCHEMBL9340512 | 0.62 | HTR2A (0.38) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814079-B1 | Triazole derivative or salt thereof | SS PHARMACEUTICAL CO (JP) | 2001-03-28 | — | — | EP | disclosed |
| US-6063945-A | FUNGICIDES | SS PHARMACEUTICAL CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5939448-A | ANTIMYCOTIC AGENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0814079-A1 | Triazole derivative or salt thereof | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-12-29 | — | — | EP | disclosed |