Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.34 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803860 | 0.83 | BACE1 (0.36) | BACE1CTSDBACE2 | |
| SCHEMBL6942401 | 0.83 | BACE1 (0.34) | BACE1BACE2ALDH1A1 | |
| SCHEMBL7804436 | 0.79 | MAPK14 (0.35) | BACE1HCAR3HCAR2BACE2ALDH1A1 | |
| SCHEMBL6941023 | 0.79 | SLC6A3 (0.34) | — | |
| SCHEMBL7894895 | 0.77 | BACE1 (0.34) | BACE1CTSDBACE2KCNH2 | |
| SCHEMBL6942412 | 0.77 | SLC6A4 (0.37) | ALDH1A1 | |
| SCHEMBL7797796 | 0.75 | BACE1 (0.41) | BACE1 | |
| SCHEMBL7799833 | 0.74 | HCAR3 (0.36) | BACE1CTSDHCAR3HCAR2BACE2 | |
| SCHEMBL7808783 | 0.72 | BACE1 (0.39) | BACE1CTSDHCAR3HCAR2BACE2 | |
| SCHEMBL8871864 | 0.72 | MAPT (0.42) | HCAR3HCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927719-B1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6204415-B1 | 2,2-DIFLUORO-2-ETHYLTHIOACETOPHENONE DERIVATIVES OF GIVEN FORMULA WHICH HAVE USE AS INTERMEDIATES TO ANTIMYCOTIC AGENTS | SSP CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| US-6194592-B1 | AS ANTIMYCOTIC AGENT | SSP CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| US-6083968-A | A FUNGICIDE; 1,1-DIFLUORO-1-ETHYL THIENYL OR ETHYL THIENYL OXIDES-2-(2,4-SUBSTITUTED PHENYL)-3-(1H-1,2,4-TRIA ZOL-1-YL)-2-OXY OR HYDROXY COMPOUND | SSP CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0927719-A1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |