Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942401 | 0.86 | BACE1 (0.34) | ALDH1A1BACE1BACE2 | |
| SCHEMBL7803860 | 0.84 | BACE1 (0.36) | BACE1BACE2 | |
| SCHEMBL6942499 | 0.79 | BACE1 (0.34) | HCAR3HCAR2ALDH1A1BACE1BACE2 | |
| SCHEMBL7797796 | 0.78 | BACE1 (0.41) | BACE1 | |
| SCHEMBL8871864 | 0.74 | MAPT (0.42) | MAPK14HCAR3HCAR2ALDH1A1MAPT | |
| SCHEMBL8872349 | 0.73 | MAPT (0.41) | MAPK14HCAR3HCAR2ALDH1A1MAPT | |
| SCHEMBL7804475 | 0.72 | CES2 (0.41) | ALDH1A1MAPTTSHRTDP1MAOB | |
| SCHEMBL7808769 | 0.71 | MAPT (0.39) | MAPK14HCAR3HCAR2ALDH1A1MAPT | |
| SCHEMBL7894895 | 0.71 | BACE1 (0.34) | CYP2D6BACE1BACE2 | |
| SCHEMBL8446160 | 0.71 | NPSR1 (0.44) | MAPK14HCAR3HCAR2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814079-B1 | Triazole derivative or salt thereof | SS PHARMACEUTICAL CO (JP) | 2001-03-28 | — | — | EP | disclosed |
| US-6063945-A | FUNGICIDES | SS PHARMACEUTICAL CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5939448-A | ANTIMYCOTIC AGENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0814079-A1 | Triazole derivative or salt thereof | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-12-29 | — | — | EP | disclosed |