Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 8/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805235 | 0.88 | BACE1 (0.32) | BACE1BACE2CTSDHCAR3HCAR2 | |
| SCHEMBL7810535 | 0.84 | TDP1 (0.35) | BACE1BACE2CTSD | |
| SCHEMBL7799833 | 0.80 | HCAR3 (0.36) | BACE1BACE2CTSDHCAR3HCAR2 | |
| SCHEMBL7803860 | 0.76 | BACE1 (0.36) | BACE1BACE2CTSD | |
| SCHEMBL7808769 | 0.75 | MAPT (0.39) | HCAR3HCAR2 | |
| SCHEMBL8872349 | 0.74 | MAPT (0.41) | HCAR3HCAR2 | |
| SCHEMBL8871864 | 0.73 | MAPT (0.42) | HCAR3HCAR2 | |
| SCHEMBL6942499 | 0.72 | BACE1 (0.34) | BACE1BACE2CTSDHCAR3HCAR2 | |
| SCHEMBL8872486 | 0.69 | HCAR3 (0.39) | BACE1BACE2HCAR3HCAR2 | |
| SCHEMBL20030227 | 0.68 | ACLY (0.31) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819124-B1 | AZOLE COMPOUNDS WITH ANTIMYCOTIC ACTIVITY FOR HUMAN AND VETERINARY USE | ZAMBON SPA (IT) | 2001-10-31 | — | — | EP | disclosed |