Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.49 |
| ▸ | CCR9 | P51686 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394272 | 0.89 | ALOX5 (0.54) | FFAR1TDP1L3MBTL1TRPM8SLC5A1 | |
| SCHEMBL16416582 | 0.84 | ESR1 (0.50) | FFAR1TDP1L3MBTL1KMT2ASLC5A1 | |
| SCHEMBL11132861 | 0.82 | RAB9A (0.51) | FFAR1KMT2ACCR9ALDH1A1HTT | |
| SCHEMBL3139297 | 0.82 | TAAR1 (0.52) | FFAR1KMT2ATAAR1 | |
| SCHEMBL9242991 | 0.82 | GFER (0.48) | FFAR1L3MBTL1KMT2AHTT | |
| SCHEMBL4425976 | 0.82 | TAAR1 (0.52) | FFAR1TDP1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL21246195 | 0.82 | L3MBTL1 (0.46) | FFAR1TDP1L3MBTL1TRPM8KMT2A | |
| SCHEMBL3366949 | 0.82 | KMT2A (0.70) | FFAR1TDP1L3MBTL1KMT2AALDH1A1 | |
| Water SCHEMBL3678915 | 0.80 | KMT2A (0.68) | FFAR1TDP1L3MBTL1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3136984 | 0.80 | KMT2A (0.68) | FFAR1TDP1L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736134-B | (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof | 浙江工业大学台州研究院 | 2023-06-06 | — | — | CN | disclosed |
| CN-111960962-B | Nickel-catalyzed alpha-alkylation method of acetamide and thioacetamide | 山东师范大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-114736134-A | (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof | 浙江工业大学台州研究院 | 2022-07-12 | — | — | CN | disclosed |
| CN-111960962-A | Nickel-catalyzed alpha-alkylation method of acetamide and thioacetamide | 山东师范大学 | 2020-11-20 | — | — | CN | disclosed |
| EP-2655357-B1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO SA (CH) | 2016-06-22 | — | — | EP | disclosed |
| US-20130109652-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | ADDEX PHARMACEUTICALS S.A. (CH) | 2013-05-02 | — | — | US | disclosed |
| US-20130109652-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | ADDEX PHARMACEUTICALS S.A. (CH) | 2013-05-02 | — | — | US | disclosed |
| US-8399493-B2 | Pyridinone derivatives and their use as positive allosteric modulators of mGluR2-receptors | Janssen Pharmaceuticals, Inc. (US) | 2013-03-19 | — | — | US | disclosed |
| EP-1523473-B1 | INDOLINE DERIVATIVES SUBSTITUTED IN POSITION 6, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2013-02-27 | — | — | EP | disclosed |
| WO-2012084704-A1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO S.A. (CH) | 2012-06-28 | — | — | WO | disclosed |
| US-20070213323-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | Janssen Pharmaceuticals, Inc. | 2007-09-13 | — | — | US | disclosed |
| EP-0814382-B1 | Improved photoresists and method for making printing plates | PRINTING DEV INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-5962192-A | FILM FORMING POLYMER, AN ORGANO AZIDE AND A PHOTOSENSITIVE DYE THAT ABSORBS LIGHT AT THE FREQUENCY OF THE PATTERNING LASER AND CONVERTS IT TO HEAT ENERGY. THE HEAT ENERGY IN TURN ELEVATES THE TEMPERATURE OF THE ORGANO AZIDE ABOVE ITS | PRINTING DEVELOPMENTS, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0814382-A1 | Improved photoresists and method for making printing plates | PRINTING DEVELOPMENTS INC (US) | 1997-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213323-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | GRM2, GRM1, GRM3 | FFAR1 162/4885TDP1 2586/4885L3MBTL1 4718/4885 |
| US-20130109652-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | GRM2, GRM1, GRIA2 | FFAR1 169/4885TDP1 3094/4885L3MBTL1 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.