Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.43 |
| ▸ | ITGAV | P06756 | 8/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182503 | 0.95 | TGM2 (0.47) | TGM2ITGB3ITGAVCTRB1ITGA2B | |
| SCHEMBL7796404 | 0.95 | TGM2 (0.47) | TGM2ITGB3ITGAVCTRB1ITGA2B | |
| SCHEMBL7789622 | 0.90 | CYP3A4 (0.50) | TGM2ITGB3ITGAVITGA2BCTSL | |
| SCHEMBL7800262 | 0.89 | CTSL (0.46) | TGM2ITGB3ITGAVCTRB1ITGA2B | |
| SCHEMBL7796565 | 0.88 | ATM (0.48) | POLBTGM2ITGB3ITGAVITGA2B | |
| SCHEMBL7796555 | 0.87 | TGM2 (0.41) | TGM2ITGB3ITGAVCTRB1ITGA2B | |
| SCHEMBL7800198 | 0.86 | PSMB5 (0.40) | TGM2ITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL7797932 | 0.86 | MMP8 (0.39) | TGM2ITGB3ITGAVITGA2BATM | |
| SCHEMBL7800098 | 0.85 | ITGB3 (0.40) | TGM2ITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL7797836 | 0.84 | NPC1 (0.38) | POLBTGM2ITGB3ITGAVALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748801-B1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEM (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6018069-A | 2-isoxazoline derivative and process for producing the same and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5994558-A | 2-isoxazoline derivative and process for producing the same; and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5962692-A | 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5750717-A | 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0748801-A1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |