Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797988 | 0.77 | HTT (0.48) | HTTTDP1P2RX7MAPK1ALDH1A1 | |
| SCHEMBL28467654 | 0.77 | NLRP3 (0.42) | MAPK1ALDH1A1TTRAKR1B10UGT1A9 | |
| SCHEMBL3396111 | 0.77 | KMT2A (0.43) | P2RX7MAPK1TTRAKR1B10UGT1A9 | |
| SCHEMBL248113 | 0.77 | ALDH1A1 (0.65) | MAPK1ALDH1A1L3MBTL1PAMKMT2A | |
| SCHEMBL28535131 | 0.76 | KMT2A (0.42) | P2RX7MAPK1TTRAKR1B10UGT1A9 | |
| SCHEMBL3636581 | 0.76 | KMT2A (0.42) | P2RX7MAPK1TTRAKR1B10UGT1A9 | |
| SCHEMBL11408628 | 0.76 | HTT (0.47) | HTTTDP1P2RX7MAPK1ALDH1A1 | |
| SCHEMBL27465829 | 0.75 | P2RX7 (0.43) | HTTTDP1P2RX7MAPK1ALDH1A1 | |
| SCHEMBL8370090 | 0.74 | KMT2A (0.57) | HTTTDP1MAPK1ALDH1A1L3MBTL1 | |
| Acetic Acid SCHEMBL28825732 | 0.73 | HTT (0.45) | HTTTDP1P2RX7MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082290-A1 | PROCESS FOR THE PREPARATION OF ACECLOFENAC | RUSSINSKY LIMITED (IE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999055660-A1 | PROCESS FOR THE PREPARATION OF ACECLOFENAC | RUSSINSKY LIMITED (IE) | 1999-11-04 | — | — | WO | disclosed |