Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8031631 | 0.99 | HTR1D (0.32) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL8035283 | 0.87 | HTR1D (0.32) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| SCHEMBL7804915 | 0.76 | HTR2A (0.33) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| SCHEMBL6609182 | 0.74 | PRKCI (0.51) | CYP1A2CYP2C9HTR2AHTR2C | |
| SCHEMBL8447037 | 0.72 | HTR1D (0.39) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| SCHEMBL7808748 | 0.72 | HTR1D (0.34) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| SCHEMBL3332580 | 0.72 | HTR2C (0.52) | CYP1A2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8031125 | 0.71 | HTR1D (0.33) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| SCHEMBL7798145 | 0.70 | KMO (0.35) | HTR1DHTR1BCYP1A2CYP2C9LMNA | |
| SCHEMBL7798188 | 0.70 | HTR2C (0.54) | HTR1DHTR1BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |