Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LOX | P28300 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798812 | 0.82 | LMNA (0.51) | ALDH1A1GAAMEN1KMT2ALOX | |
| Tetraxetan SCHEMBL861961 | 0.81 | SLC6A9 (0.49) | ALDH1A1GAAPOLBSMN1; SMN2TDP1 | |
| SCHEMBL56319 | 0.80 | LOX (0.57) | ALDH1A1GAAMEN1KMT2ALOX | |
| SCHEMBL5261643 | 0.78 | KMT2A (0.72) | ALDH1A1GAAMEN1KMT2ALOX | |
| SCHEMBL6550220 | 0.76 | SIGMAR1 (0.60) | ALDH1A1MEN1KMT2AMAPK1TSHR | |
| SCHEMBL7874006 | 0.73 | HTT (0.62) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL14304331 | 0.73 | LOX (0.60) | ALDH1A1GAALOXTSHREPHX2 | |
| SCHEMBL15651574 | 0.72 | LTA4H (0.60) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8655258 | 0.72 | LMNA (0.59) | ALDH1A1MAPK1 | |
| SCHEMBL13723844 | 0.72 | MAPT (0.59) | ALDH1A1GAAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888406-B1 | AZO COMPOUNDS | AVECIA LTD (GB) | 2001-12-12 | — | — | EP | disclosed |
| US-6008331-A | USEFUL AS BLACK COLORANTS FOR INK JET PRINTING INKS | ZENECA LIMITED (GB) | 1999-12-28 | — | — | US | disclosed |
| EP-0888406-A1 | AZO COMPOUNDS | ZENECA LIMITED (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032931-A1 | AZO COMPOUNDS | ZENECA LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |