Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797154 | 0.76 | HDAC6 (0.42) | HDAC6ALDH1A1POLBPKM | |
| SCHEMBL1174050 | 0.76 | HDAC6 (0.62) | HDAC6ALDH1A1POLBPKM | |
| SCHEMBL1173906 | 0.74 | HDAC6 (0.62) | HDAC6ALDH1A1POLBPKM | |
| SCHEMBL7796483 | 0.74 | HDAC6 (0.47) | HDAC6 | |
| SCHEMBL7795811 | 0.74 | POLB (0.40) | HDAC6ALDH1A1POLB | |
| SCHEMBL7796728 | 0.74 | HDAC1 (0.53) | HDAC6 | |
| SCHEMBL7796324 | 0.72 | HDAC6 (0.63) | HDAC6 | |
| SCHEMBL7787409 | 0.72 | HDAC6 (0.47) | HDAC6ALDH1A1 | |
| SCHEMBL7796971 | 0.72 | ALDH1A1 (0.43) | HDAC6ALDH1A1POLB | |
| SCHEMBL7796321 | 0.72 | HDAC6 (0.50) | HDAC6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |