Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13387445 | 0.87 | FAAH (0.58) | LMNAFAAHSMN1; SMN2 | |
| SCHEMBL6518969 | 0.86 | TSHR (0.55) | LMNAGAAEPHX1CYP2C9CYP2C19 | |
| SCHEMBL8590341 | 0.81 | CYP1A2 (0.55) | LMNAFAAHCYP2C19SMN1; SMN2 | |
| SCHEMBL15738567 | 0.81 | FAAH (0.53) | FAAH | |
| SCHEMBL14861111 | 0.81 | GAA (0.58) | MAPTGAAEPHX1CYP2C9CYP2C19 | |
| SCHEMBL10944355 | 0.81 | MAPT (0.80) | MGLLMEN1MAPTKMT2ALMNA | |
| SCHEMBL4798471 | 0.81 | MGLL (0.63) | MGLLMEN1MAPTKMT2ALMNA | |
| SCHEMBL27795672 | 0.80 | LMNA (0.56) | MAPTLMNAALDH1A1FAAHCYP2C9 | |
| SCHEMBL16696334 | 0.80 | FAAH (0.56) | KMT2ALMNAGAAALDH1A1FAAH | |
| SCHEMBL2094718 | 0.80 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1FAAHCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683155-A | Novel diamine, polyamic acid, and polyimide | 日产化学工业株式会社 | 2016-06-15 | — | — | CN | disclosed |
| EP-1163220-A1 | TRICYCLIC INDOLE-2-CARBOXYLIC ACID COMPOUND USED AS NMDA RECEPTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056711-A1 | TRICYCLIC INDOLE-2-CARBOXYLIC ACID COMPOUND USED AS NMDA RECEPTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-09-28 | — | — | WO | disclosed |