Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804738 | 0.83 | PDE4A (0.38) | PRMT5WDR77 | |
| SCHEMBL7799316 | 0.83 | HSD11B1 (0.31) | — | |
| SCHEMBL7808215 | 0.82 | PDE4A (0.37) | PRMT5WDR77 | |
| SCHEMBL7804691 | 0.82 | PDE4A (0.37) | PRMT5WDR77 | |
| SCHEMBL7808213 | 0.82 | PDE4A (0.37) | PRMT5WDR77 | |
| SCHEMBL7809902 | 0.78 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL7806059 | 0.78 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL8107979 | 0.77 | NR1H2 (0.36) | — | |
| SCHEMBL9595771 | 0.77 | NR1H2 (0.36) | — | |
| SCHEMBL4293924 | 0.77 | NR1H2 (0.32) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773222-B1 | CARBAPENEM DERIVATIVE | EISAI CO LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6037341-A | HAVING POTENT ANTIMICROBIAL EFFECTS OVER GRAM-POSITIVE BACTERIA AND GRAM-NEGATIVE BACTERIA | EISAI CO., LTD. (JP) | 2000-03-14 | — | — | US | disclosed |
| EP-0773222-A1 | NOVEL CARBAPENEM DERIVATIVE | Eisai Co., Ltd. (JP) | 1997-05-14 | — | — | EP | disclosed |