Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806059 | 1.00 | PRMT5 (0.36) | PRMT5WDR77DPP4RECQLHPGD | |
| SCHEMBL7799282 | 0.94 | PRMT5 (0.38) | PRMT5WDR77HPGDPDE4BUSP30 | |
| SCHEMBL7804738 | 0.80 | PDE4A (0.38) | PRMT5WDR77PDE4B | |
| SCHEMBL7804688 | 0.80 | GPR119 (0.40) | PRMT5WDR77GPR119JAK2JAK1 | |
| SCHEMBL7804691 | 0.79 | PDE4A (0.37) | PRMT5WDR77PDE4BHSD17B10 | |
| SCHEMBL7808213 | 0.79 | PDE4A (0.37) | PRMT5WDR77PDE4BHSD17B10 | |
| SCHEMBL7808215 | 0.79 | PDE4A (0.37) | PRMT5WDR77PDE4BHSD17B10 | |
| SCHEMBL7799295 | 0.78 | VHL (0.31) | PRMT5WDR77 | |
| SCHEMBL9020185 | 0.78 | JAK2 (0.42) | RECQLHPGDGPR119JAK2JAK1 | |
| SCHEMBL9595771 | 0.78 | NR1H2 (0.36) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773222-B1 | CARBAPENEM DERIVATIVE | EISAI CO LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6037341-A | HAVING POTENT ANTIMICROBIAL EFFECTS OVER GRAM-POSITIVE BACTERIA AND GRAM-NEGATIVE BACTERIA | EISAI CO., LTD. (JP) | 2000-03-14 | — | — | US | disclosed |
| EP-0773222-A1 | NOVEL CARBAPENEM DERIVATIVE | Eisai Co., Ltd. (JP) | 1997-05-14 | — | — | EP | disclosed |