Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496547 | 0.91 | MAPT (0.67) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1606348 | 0.91 | MAPT (0.67) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29834220 | 0.91 | MAPT (0.67) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24779254 | 0.90 | MAPT (0.51) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29407955 | 0.86 | CA1 (0.44) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6565552 | 0.86 | CA1 (0.44) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL301296 | 0.86 | CA1 (0.44) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL29430119 | 0.86 | CA1 (0.44) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL1768301 | 0.85 | CA1 (0.43) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL15658563 | 0.83 | MAPT (0.58) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49036-E1 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2022-04-19 | — | — | US | disclosed |
| EP-3489213-B1 | COMPOSITION FOR USE IN A METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2021-04-28 | — | — | EP | disclosed |
| US-10450261-B2 | Method for the homogeneous catalytic reductive amination of carbonyl compounds | BASF SE (DE) | 2019-10-22 | — | — | US | disclosed |
| EP-3489213-A1 | COMPOSITION FOR USE IN A METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2019-05-29 | — | — | EP | disclosed |
| US-10301244-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2019-05-28 | — | — | US | disclosed |
| EP-3233778-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2019-02-20 | — | — | EP | disclosed |
| US-20180186725-A1 | METHOD FOR THE HOMOGENEOUS CATALYTIC REDUCTIVE AMINATION OF CARBONYL COMPOUNDS | BASF SE (DE) | 2018-07-05 | — | — | US | disclosed |
| US-9975837-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2018-05-22 | — | — | US | disclosed |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-06-22 | — | — | US | disclosed |
| US-7534921-B2 | Method for the production of optically active carbonyl | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-19 | — | — | US | disclosed |
| US-7534921-B2 | Method for the production of optically active carbonyl | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-19 | — | — | US | disclosed |
| US-20080269528-A1 | Method for the Production of Optically Active Carbonyl | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269528-A1 | Method for the Production of Optically Active Carbonyl | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080139852-A1 | Method For The Production Of Menthol | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080139852-A1 | Method For The Production Of Menthol | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080108117-A1 | Method for Producing an Optically Active 2-Methyl-Alkane-1-Ol from the Corresponding 2-Methylalk-2-En-1-Al, Comprising Carbonyl-Selective Reduction, Enantioselective Hydration and Lipase-Catalyzed Stereoselective Acylation in Order to Enrich the Desired | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080108117-A1 | Method for Producing an Optically Active 2-Methyl-Alkane-1-Ol from the Corresponding 2-Methylalk-2-En-1-Al, Comprising Carbonyl-Selective Reduction, Enantioselective Hydration and Lipase-Catalyzed Stereoselective Acylation in Order to Enrich the Desired | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
| WO-2007082927-A1 | CHEMICAL TRANSFORMATION PROCESS IN THE PRESENCE OF A RUTHENIUM CATALYST | BASF SE (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082928-A2 | METHOD FOR PRODUCTION OF A RUTHENIUM CATALYST | BASF SE (DE) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | POF1B, FGFR1, COASY | MAPT 4198/4885KMT2A 2292/4885MEN1 3486/4885 |
| US-20180186725-A1 | METHOD FOR THE HOMOGENEOUS CATALYTIC REDUCTIVE AMINATION OF CARBONYL COMPOUNDS | CAT, AOC1, CYCS | MAPT 3635/4885KMT2A 257/4885MEN1 1933/4885 |
| US-10301244-B2 | Method for synthesizing optically active carbonyl compounds | CBR3, CBR1, HRH4 | MAPT 4602/4885KMT2A 4289/4885MEN1 809/4885 |
| US-20080269528-A1 | Method for the Production of Optically Active Carbonyl | CBR1, CBR3, HMOX1 | MAPT 2045/4885KMT2A 3747/4885MEN1 2981/4885 |
| US-10450261-B2 | Method for the homogeneous catalytic reductive amination of carbonyl compounds | CAT, AOC1, CYCS | MAPT 3635/4885KMT2A 257/4885MEN1 1933/4885 |
| US-20080139852-A1 | Method For The Production Of Menthol | NISCH, CYP8B1, MSMO1 | MAPT 870/4885KMT2A 4538/4885MEN1 667/4885 |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | CBR3, CBR1, HRH4 | MAPT 4602/4885KMT2A 4289/4885MEN1 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.