Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215323 | 0.78 | ALDH1A1 (0.56) | MEN1KMT2ASMN1; SMN2CYP3A4MAPT | |
| SCHEMBL7799349 | 0.78 | NR4A2 (0.61) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL29797867 | 0.77 | NPC1 (0.56) | SMN1; SMN2KDM4EMAPTCES1NPC1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.77 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2CYP3A4HPGD | |
| Dibenzoylmethane SCHEMBL39582 | 0.77 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2CYP3A4HPGD | |
| Dibenzoylmethane SCHEMBL1704711 | 0.77 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2CYP3A4HPGD | |
| SCHEMBL8392453 | 0.76 | MAOB (0.57) | KMT2ASMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL14757597 | 0.76 | MAOB (0.57) | KMT2ASMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL11219615 | 0.75 | MAOB (0.53) | KMT2ASMN1; SMN2NPC1RAB9APKM | |
| Dibenzoylmethane SCHEMBL14249870 | 0.74 | MEN1 (0.94) | MEN1KMT2ASMN1; SMN2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5118681-A | Bactericides | ROHM AND HAAS COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |