Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808200 | 1.00 | OPRM1 (0.31) | OPRM1OPRD1SIGMAR1SLC18A3USP2 | |
| Hydrochloric Acid SCHEMBL8389564 | 0.98 | DRD2 (0.31) | OPRM1OPRD1 | |
| Oxalic Acid SCHEMBL7799421 | 0.89 | DRD2 (0.35) | OPRM1OPRD1SIGMAR1SLC18A3 | |
| Oxalic Acid SCHEMBL7799419 | 0.89 | DRD2 (0.35) | OPRM1OPRD1SIGMAR1SLC18A3 | |
| SCHEMBL24114621 | 0.81 | LMNA (0.48) | OPRM1OPRD1SIGMAR1SLC18A3USP2 | |
| SCHEMBL24114565 | 0.81 | LMNA (0.48) | OPRM1OPRD1SIGMAR1SLC18A3USP2 | |
| SCHEMBL4851968 | 0.79 | SLC6A3 (0.43) | OPRM1OPRD1 | |
| SCHEMBL25646811 | 0.79 | OPRM1 (0.34) | OPRM1OPRD1SIGMAR1SLC18A3 | |
| SCHEMBL8282067 | 0.76 | SLC6A3 (0.41) | — | |
| SCHEMBL24455952 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |