Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687772 | 0.78 | GPR3 (0.45) | GPR3TRPV1 | |
| SCHEMBL8131840 | 0.77 | GPR3 (0.36) | GPR3CHRM5 | |
| SCHEMBL8123785 | 0.77 | GPR3 (0.41) | GPR3CHRM5PDK2 | |
| SCHEMBL8143605 | 0.74 | P2RY1 (0.35) | GPR3 | |
| SCHEMBL8128913 | 0.73 | DHODH (0.39) | GPR3CHRM5P2RX1MAPTTRPV1 | |
| SCHEMBL8125229 | 0.72 | METAP2 (0.38) | GPR3CHRM5NOTUM | |
| SCHEMBL7685104 | 0.72 | GPR3 (0.39) | GPR3PIM1PIM2GRIN2B | |
| SCHEMBL407097 | 0.71 | GPR3 (0.40) | GPR3CHRM5P2RX1MPIMAPT | |
| SCHEMBL8115119 | 0.69 | CETP (0.38) | P2RX7GRIA1CACNG8 | |
| SCHEMBL5670544 | 0.68 | MEN1 (0.40) | GPR3PIM1CSNK2A2CSNK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535548-B1 | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL IND LTD (JP) | 2001-11-21 | — | — | EP | claimed |