SCHEMBL5670544

SCHEMBL5670544

COc1cc[c]c(-c2ccccc2Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALOX15 P16050 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CCNE2 O96020 1/20 0.38
CCNE1 P24864 1/20 0.38
CDK2 P24941 1/20 0.38
PDE2A O00408 1/20 0.38
PDE10A Q9Y233 1/20 0.38
NFE2L2 Q16236 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
LMNA P02545 2/20 0.37
CASP3 P42574 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
CASR P41180 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528792 0.81 ALDH1A1 (0.44) MEN1KMT2ARAB9AALDH1A1MAPT
SCHEMBL8125196 0.81 CYP1A2 (0.40) MEN1KMT2AALOX15NPC1RAB9A
SCHEMBL17999104 0.81 ACHE (0.37) L3MBTL1PDE2APDE10ANFE2L2ALDH1A1
SCHEMBL8123605 0.80 RAB9A (0.46) MEN1KMT2ANPC1RAB9AL3MBTL1
SCHEMBL15066961 0.78 ALDH1A1 (0.41) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL7067601 0.78 CYP1A2 (0.42) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL9568033 0.78 ACHE (0.37) MEN1KMT2ANPC1RAB9AL3MBTL1
SCHEMBL10437518 0.78 GPR3 (0.35) MEN1KMT2ANPC1RAB9AL3MBTL1
SCHEMBL9138237 0.77 HSD11B1 (0.41) MEN1KMT2ANPC1RAB9APDE2A
SCHEMBL7839044 0.77 PLA2G7 (0.40) MEN1KMT2AALOX15NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060188790-A1 Hologram recording material, hologram recording method, and optical recording medium FUJI PHOTO FILM CO., LTD. 2006-08-24 US disclosed
US-4946493-A FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-08-07 US disclosed
US-4845250-A FUNGICIDES, PLANT GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-07-04 US disclosed
US-4524168-A AZO DYES CIBA-GEIGY CORPORATION (US) 1985-06-18 US disclosed
US-4507140-A GALLIUM ARSENIDE DOPED WITH GERMANIUM AND TELLURIUM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-03-26 US disclosed