Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 4/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131840 | 0.88 | GPR3 (0.36) | GPR3CHRM5S1PR1KIF11SCN9A | |
| SCHEMBL7687772 | 0.83 | GPR3 (0.45) | GPR3KIF11FFAR4 | |
| SCHEMBL8125196 | 0.81 | CYP1A2 (0.40) | GPR3 | |
| SCHEMBL8128678 | 0.78 | LTA4H (0.39) | — | |
| SCHEMBL8125229 | 0.78 | METAP2 (0.38) | GPR3CHRM5KIF11 | |
| SCHEMBL8129685 | 0.77 | PDE10A (0.36) | GPR3PDE10A | |
| SCHEMBL7799755 | 0.77 | P2RX7 (0.38) | GPR3CHRM5PDK2 | |
| SCHEMBL8143605 | 0.76 | P2RY1 (0.35) | GPR3KIF11 | |
| SCHEMBL9523594 | 0.74 | NPC1 (0.40) | PDE10A | |
| SCHEMBL538958 | 0.73 | GPR3 (0.41) | GPR3KIF11SCN9ASCN5AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028945-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | Amgen Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024404-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | AMGEN INC. (US) | 1999-05-20 | — | — | WO | disclosed |