Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.70 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.70 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793938 | 0.85 | ADRA1A (0.75) | ADRA1AADRA1BADRA1DCYP3A4ADRA2A | |
| SCHEMBL6375436 | 0.83 | ADRA1A (1.00) | ADRA1AADRA1BADRA1DCYP3A4ADRA2A | |
| SCHEMBL7803674 | 0.81 | ADRA1A (0.69) | ADRA1AADRA1BADRA1DCYP3A4ADRA2A | |
| SCHEMBL7803795 | 0.81 | ADRA1B (0.72) | ADRA1AADRA1BADRA1DCYP3A4ADRA2A | |
| SCHEMBL7732089 | 0.75 | ALDH1A1 (0.60) | MAPTHTR1ALMNAMAPK1DRD2 | |
| SCHEMBL25797045 | 0.75 | ALDH1A1 (0.57) | ADRA1AADRA1BADRA1DMAPTHTR1A | |
| SCHEMBL7733972 | 0.75 | ALDH1A1 (0.60) | ADRA1AADRA1BADRA1DMAPTHTR1A | |
| SCHEMBL7799623 | 0.74 | ADRA1A (0.83) | ADRA1AADRA1BADRA1DCYP3A4ADRA2A | |
| SCHEMBL3176190 | 0.74 | ALDH1A1 (0.67) | MAPTHTR1ALMNAMAPK1DRD2 | |
| SCHEMBL7799617 | 0.73 | ADRA1B (0.74) | ADRA1AADRA1BADRA1DCYP3A4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796251-B1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6046329-A | Uracil derivatives | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-04-04 | — | — | US | disclosed |
| EP-0796251-A1 | URACIL DERIVATIVES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017831-A1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-06-13 | — | — | WO | disclosed |