Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 7/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | TNF | P01375 | 5/20 | 0.58 |
| ▸ | TNFSF11 | O14788 | 4/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12908807 | 0.90 | HTR6 (0.62) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL27622290 | 0.86 | LMNA (0.72) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL4926276 | 0.84 | LMNA (0.74) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL948989 | 0.84 | AKR1C3 (0.83) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL8998784 | 0.81 | LMNA (0.74) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL30393652 | 0.81 | LMNA (1.00) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL949716 | 0.81 | LMNA (1.00) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL13485750 | 0.79 | PLK1 (0.78) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL9591955 | 0.79 | LMNA (0.70) | LMNASMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL2886421 | 0.78 | KMT2A (1.00) | LMNASMN1; SMN2PLK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001097948-A | COMPOUND HAVING AFFINITY FOR THROMBOPOIETIN RECEPTOR | TORII YAKUHIN KK | 2001-04-10 | — | — | JP | disclosed |