Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | TNF | P01375 | 3/20 | 0.61 |
| ▸ | TNFSF11 | O14788 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 8/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR1F | P30939 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799771 | 0.86 | LMNA (0.68) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL27622286 | 0.85 | AKR1C3 (0.57) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL949716 | 0.84 | LMNA (1.00) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL19068172 | 0.84 | KMT2A (0.57) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL30393652 | 0.84 | LMNA (1.00) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL948989 | 0.84 | AKR1C3 (0.83) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL4926276 | 0.81 | LMNA (0.74) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL8998784 | 0.81 | LMNA (0.74) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL8999130 | 0.81 | PLK1 (1.00) | LMNASMN1; SMN2KMT2APLK1MEN1 | |
| SCHEMBL2886421 | 0.81 | KMT2A (1.00) | LMNASMN1; SMN2KMT2APLK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198869-A | Oxazoline derivative and preparation method and application of oxazoline derivative and prepartion method in preparing antibacterial agent of plant pathogenic fungi | UNIV HENAN SCIENCE & TECH | 2015-12-30 | — | — | CN | disclosed |
| CN-101544592-B | Process for preparation of N-arylsulfonyl-3-substituted indoles | SUVEN LIFE SCIENCES LTD | 2013-08-21 | — | — | CN | disclosed |
| CN-1720225-B | N-arylsulfonyl-3-substituted indoles having 5-hydroxytryptamine receptor affinity, process for their preparation and pharmaceutical compositions containing them | SUVEN LIFE SCIENCES LTD | 2011-05-18 | — | — | CN | disclosed |
| CN-101544592-A | N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them | SUVEN LIFE SCIENCES LTD (IN) | 2009-09-30 | — | — | CN | disclosed |
| CN-1720225-A | N-arylsulfonyl-3-substituted indoles having 5-hydroxytryptamine receptor affinity, process for their preparation and pharmaceutical compositions containing them | SUVEN LIFE SCIENCES LTD (IN) | 2006-01-11 | — | — | CN | disclosed |