Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969702 | 0.89 | PDK1 (0.40) | PDK1POLBTDP1KMT2AMEN1 | |
| SCHEMBL10976812 | 0.84 | CASP6 (0.51) | POLBTDP1KMT2AMEN1RAB9A | |
| SCHEMBL20596664 | 0.81 | PARP1 (0.54) | POLBTDP1KMT2AMEN1RAB9A | |
| SCHEMBL8651501 | 0.80 | PDK1 (0.39) | PDK1POLBTDP1KMT2AMEN1 | |
| SCHEMBL7797897 | 0.80 | PRMT5 (0.43) | POLBKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL6035964 | 0.79 | PRMT5 (0.41) | POLBKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8649043 | 0.78 | PDK1 (0.33) | PDK1TDP1KMT2AMEN1RAB9A | |
| SCHEMBL6657903 | 0.78 | PDK1 (0.38) | PDK1POLBTDP1KMT2AMEN1 | |
| SCHEMBL1018568 | 0.78 | VCAM1 (0.58) | PDK1POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9228976 | 0.78 | MAPT (0.38) | POLBTDP1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149176-A1 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | THE UNIVERSITY OF VERMONT (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1149176-A4 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | UNIV VERMONT (US) | 2001-10-31 | — | — | EP | claimed |
| US-6124099-A | Method for placing a photo-cross-linking agent at specific internal sites within the sequence of synthetic strands of ribonucleic acids | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2000-09-26 | — | — | US | claimed |
| WO-1999067424-A1 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | UNIVERSITY OF VERMONT (US) | 1999-12-29 | — | — | WO | claimed |
| EP-1149176-A4 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | UNIV VERMONT (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-1149176-A1 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | THE UNIVERSITY OF VERMONT (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6124099-A | Method for placing a photo-cross-linking agent at specific internal sites within the sequence of synthetic strands of ribonucleic acids | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999067424-A1 | A METHOD FOR PLACING A PHOTO-CROSS-LINKING AGENT AT SPECIFIC INTERNAL SITES WITHIN THE SEQUENCE OF SYNTHETIC STRANDS OF RIBONUCLEIC ACIDS | UNIVERSITY OF VERMONT (US) | 1999-12-29 | — | — | WO | disclosed |
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |