SCHEMBL7800550

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3717161	0.89	HCAR3 (0.50)	HTTHCAR3MAPTALDH1A1NPC1
	SCHEMBL2342996	0.89	HTT (0.59)	HTTHCAR3MAPTALDH1A1TDP1
	SCHEMBL10790188	0.84	HTT (0.68)	HTTMAPTALDH1A1PKMTDP1
	SCHEMBL7811924	0.83	HTT (0.56)	HTTMAPTALDH1A1TDP1SMN1; SMN2
	SCHEMBL7805730	0.81	HTT (0.78)	HTTHCAR3MAPTALDH1A1TDP1
	SCHEMBL12983948	0.79	HTT (0.60)	HTTMAPTALDH1A1TDP1SMN1; SMN2
	SCHEMBL10802959	0.78	HTT (0.68)	HTTHCAR3MAPTALDH1A1PKM
	SCHEMBL2334056	0.78	HTT (0.72)	HTTHCAR3MAPTALDH1A1PKM
	SCHEMBL11526803	0.78	HTT (0.71)	HTTMAPTALDH1A1NPC1PKM
	SCHEMBL11552885	0.77	HCAR3 (0.54)	HCAR3MAPTALDH1A1NPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.