Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYBB | P04839 | 4/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808513 | 0.89 | MAPT (0.35) | L3MBTL1MAPTADRA1DADRA1A | |
| SCHEMBL7812212 | 0.84 | CFTR (0.32) | HTR1AHTR7 | |
| SCHEMBL7807625 | 0.83 | CETP (0.33) | HTR1AHTR7ADRA1DADRA1A | |
| SCHEMBL7806005 | 0.83 | ALDH1A1 (0.40) | L3MBTL1HTR1AHTR7APPADRA1D | |
| SCHEMBL6573339 | 0.79 | L3MBTL1 (0.43) | MAP4K4L3MBTL1CYBBNOX4HTR7 | |
| SCHEMBL7808473 | 0.77 | CETP (0.35) | ADRA1DADRA1A | |
| SCHEMBL7809760 | 0.76 | S100B (0.31) | — | |
| SCHEMBL7462735 | 0.76 | MAP4K4 (0.34) | MAP4K4L3MBTL1CYBBNOX4MAPT | |
| SCHEMBL7807391 | 0.76 | ALDH1A1 (0.34) | MAPTHTR1AHTR7ADRA1DADRA1A | |
| SCHEMBL7809781 | 0.74 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |