SCHEMBL7809760

SCHEMBL7809760

COCCN(CCOC)c1ccc(N)c(-c2cccn2C)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
EPHX2 P34913 1/20 0.30
CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7812212 0.90 CFTR (0.32) ALDH1A1LMNATDP1
SCHEMBL7808513 0.84 MAPT (0.35) S100BALDH1A1LMNATDP1EPHX2
SCHEMBL7806005 0.78 ALDH1A1 (0.40) ALDH1A1TDP1EPHX2
SCHEMBL7805904 0.77 PTGER4 (0.35) ALDH1A1LMNATDP1
SCHEMBL7805981 0.77 CRHR1 (0.33)
SCHEMBL7460361 0.77 S100B (0.34) S100BALDH1A1
SCHEMBL7800920 0.76 MAP4K4 (0.34)
SCHEMBL7812211 0.75 TP53 (0.35)
SCHEMBL7808473 0.75 CETP (0.35) S100BCETP
SCHEMBL6572636 0.75 CRHR1 (0.34) S100B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed