Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801147 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL9073908 | 0.84 | LMNA (0.55) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL29430132 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL1934004 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL1934113 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL12189950 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL18110097 | 0.67 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL20854310 | 0.66 | TNF (0.37) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL20858913 | 0.65 | TNF (0.38) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL8849533 | 0.65 | LMNA (0.66) | ALDH1A1KMT2AMEN1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184379-B1 | FLUORESCENT DYES USED IN DIAGNOSIS | ROCHE DIAGNOSTICS GMBH (DE) | 2001-02-06 | — | — | US | disclosed |