Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29430132 | 1.00 | ALDH1A1 (0.42) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| Bromide SCHEMBL7794743 | 0.98 | ALDH1A1 (0.41) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL20390457 | 0.88 | ALDH1A1 (0.40) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL14850036 | 0.84 | ALDH1A1 (0.54) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL3485083 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL12388029 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL29430125 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL1917162 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL15158277 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL7801140 | 0.77 | ALDH1A1 (0.40) | ALDH1A1LMNANPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262336-A | Self-flashing fluorescent dye for lysosome super-resolution fluorescence imaging and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2022-04-01 | — | — | CN | claimed |
| US-11939350-B2 | Fluorescent dyes and methods of use thereof | ENZO LIFE SCIENCES, INC. (US) | 2024-03-26 | — | — | US | disclosed |
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-11-08 | — | — | US | disclosed |
| EP-3247710-B1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | BIOSEARCH TECH INC (US) | 2022-10-19 | — | — | EP | disclosed |
| CN-114262336-A | Self-flashing fluorescent dye for lysosome super-resolution fluorescence imaging and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2022-04-01 | — | — | CN | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| CN-107207480-B | Coumarin-based compounds and related methods | 生物检索技术股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| US-7504496-B2 | Water-soluble rhodamine dye conjugates | APPLIED BIOSYSTEMS, LLC | 2009-03-17 | — | — | US | disclosed |
| US-7109043-B2 | Fluorescent probe for magnesium ion determination | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20040044228-A1 | Fluorescent probe for magnesium ion determination | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-0962497-B1 | Rhodamine derivates and their use in diagnostic systems | ROCHE DIAGNOSTICS GMBH (DE) | 2001-07-18 | — | — | EP | disclosed |
| US-6184379-B1 | FLUORESCENT DYES USED IN DIAGNOSIS | ROCHE DIAGNOSTICS GMBH (DE) | 2001-02-06 | — | — | US | disclosed |
| EP-0962497-A1 | Rhodamine derivates and their use in diagnostic systems | Roche Diagnostics GmbH (DE) | 1999-12-08 | — | — | EP | disclosed |
| US-5750409-A | MARKERS FOR HAPTEN-ANTIBODY-PROTEIN CONJUGATES | BOEHRINGER MANNHEIM GMBH (DE) | 1998-05-12 | — | — | US | disclosed |
| EP-0567622-B1 | NEW PENTACYCLIC COMPOUNDS AND THEIR USE AS ABSORPTION OR FLUORESCENCE DYES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1993010189-A1 | NEW PENTACYCLIC COMPOUNDS AND THEIR USE AS ABSORPTION OR FLUORESCENCE DYES | BOEHRINGER MANNHEIM GMBH (DE) | 1993-05-27 | — | — | WO | disclosed |
| EP-0543333-A1 | New pentacyclic compounds and their use as absorption or fluorescence dyestuffs | Roche Diagnostics GmbH (DE) | 1993-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | NTRK1, PMP22, GAP43 | ALDH1A1 813/4885LMNA 754/4885NPSR1 460/4885 |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | ALDH1A1 1305/4885LMNA 1879/4885NPSR1 396/4885 |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | NTRK1, NGF, SMN1; SMN2 | ALDH1A1 822/4885LMNA 444/4885NPSR1 878/4885 |
| US-20040044228-A1 | Fluorescent probe for magnesium ion determination | MGST1, CA2, MRM1 | ALDH1A1 1503/4885LMNA 2506/4885NPSR1 2703/4885 |
| US-11939350-B2 | Fluorescent dyes and methods of use thereof | BCDIN3D, EFTUD2, IK | ALDH1A1 245/4885LMNA 199/4885NPSR1 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.