Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292926 | 0.98 | FFAR4 (0.51) | FFAR4FFAR1PPARGPPARAGPR84 | |
| SCHEMBL8370822 | 0.95 | PLA2G2C (0.46) | FFAR4FFAR1AKR1B1PPARGPPARA | |
| SCHEMBL14166506 | 0.91 | FFAR4 (0.61) | FFAR4FFAR1AKR1B1PPARGPPARA | |
| SCHEMBL14166998 | 0.91 | FFAR4 (0.61) | FFAR4FFAR1AKR1B1PPARGPPARA | |
| SCHEMBL18114663 | 0.91 | FFAR4 (0.61) | FFAR4FFAR1AKR1B1PPARGPPARA | |
| SCHEMBL14166997 | 0.91 | FFAR4 (0.61) | FFAR4FFAR1AKR1B1PPARGPPARA | |
| SCHEMBL1593287 | 0.91 | FFAR4 (0.61) | FFAR4FFAR1AKR1B1PPARGPPARA | |
| SCHEMBL14166507 | 0.91 | FFAR4 (0.61) | FFAR4FFAR1AKR1B1PPARGPPARA | |
| SCHEMBL23429927 | 0.87 | LMNA (0.44) | FFAR4FFAR1AKR1B1GPR84TSHR | |
| SCHEMBL7694858 | 0.87 | HDAC1 (0.41) | FFAR4FFAR1AKR1B1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044539-A1 | Heterobicyclic and tricyclic nitric oxide synthase inhibitors | HANSEN DONALD W (US) | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044539-A1 | Heterobicyclic and tricyclic nitric oxide synthase inhibitors | NOS1, NOS2, NOS3 | FFAR4 2836/4885FFAR1 1541/4885AKR1B1 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.