Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059987 | 0.83 | CCR1 (0.42) | CCR1PDE10AMAPTTERTHTR2A | |
| SCHEMBL7809623 | 0.74 | S1PR4 (0.49) | CCR1S1PR4PDE10AMCHR1NOTUM | |
| SCHEMBL7808283 | 0.74 | CCR1 (0.48) | CCR1PDE10AKDM4ECYP1A2NOTUM | |
| SCHEMBL7808149 | 0.73 | HDAC1 (0.49) | CCR1S1PR4PDE10AALDH1A1MCHR1 | |
| SCHEMBL2567212 | 0.73 | BACE1 (0.53) | CCR1PDE10AKDM4EALDH1A1MAPT | |
| SCHEMBL4052149 | 0.73 | CYP1A2 (0.48) | KDM4EMAPTCYP1A2 | |
| SCHEMBL16822493 | 0.71 | CCR1 (0.48) | CCR1S1PR4KDM4EMAPTNOTUM | |
| SCHEMBL6089466 | 0.71 | TERT (0.37) | PDE10AALDH1A1TERTCYSLTR1 | |
| SCHEMBL12517340 | 0.71 | CCR1 (0.48) | CCR1S1PR4PDE10AKDM4EALDH1A1 | |
| SCHEMBL7806544 | 0.70 | CCR1 (0.44) | CCR1S1PR4KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| CN-1046279-C | Quinoline derivative | UBE INDUSTRIES (JP) | 1999-11-10 | — | — | CN | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |