Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801234 | 0.90 | THRA (0.36) | THRATHRBLMNAALDH1A1GAA | |
| SCHEMBL7780353 | 0.86 | POLB (0.34) | LMNAALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7801984 | 0.85 | CXCR2 (0.36) | THRATHRBALDH1A1MEN1KMT2A | |
| SCHEMBL7785088 | 0.85 | ALDH1A1 (0.41) | THRATHRBLMNAALDH1A1GAA | |
| SCHEMBL7780740 | 0.85 | ALDH1A1 (0.41) | THRATHRBLMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7803627 | 0.84 | ALDH1A1 (0.41) | THRATHRBLMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7795516 | 0.82 | THRA (0.37) | THRATHRBLMNAALDH1A1GAA | |
| SCHEMBL7801958 | 0.81 | MEN1 (0.39) | THRATHRBLMNAALDH1A1MEN1 | |
| SCHEMBL7795456 | 0.81 | CXCR2 (0.35) | THRATHRBLMNAALDH1A1GAA | |
| SCHEMBL7789345 | 0.79 | ALDH1A1 (0.46) | THRATHRBLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |