Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methylbenzoic Acid SCHEMBL8035699 | 0.91 | MAOB (0.43) | RXRARXRBMAOBCYP1A1CYP1B1 | |
| Benzoic Acid SCHEMBL7792805 | 0.91 | PPARA (0.43) | RXRARXRBMAOBCYP1A1CYP1B1 | |
| SCHEMBL7802496 | 0.90 | RXRA (0.46) | RXRARXRBMAOBCYP1A1CYP1B1 | |
| SCHEMBL7798600 | 0.88 | SRD5A2 (0.46) | RXRARXRBNR4A2SMN1; SMN2 | |
| SCHEMBL7801557 | 0.87 | MAOB (0.51) | RXRARXRBMAOBCYP1A1CYP1B1 | |
| Tyramine SCHEMBL8039128 | 0.86 | SRD5A2 (0.41) | RXRARXRBMAOBNR4A2RXRG | |
| Phenethylamine SCHEMBL7799012 | 0.86 | RXRA (0.42) | RXRARXRBNR4A2RXRG | |
| SCHEMBL7798427 | 0.85 | SRD5A2 (0.40) | RXRARXRBRXRG | |
| Benzoic Acid SCHEMBL7798463 | 0.84 | MAOB (0.49) | MAOBCYP1A1CYP1B1PPARANR4A2 | |
| SCHEMBL7792606 | 0.83 | KDM4E (0.45) | RXRARXRBPPARDPPARARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |