Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC3R | P41968 | 7/20 | 0.38 |
| ▸ | MC4R | P32245 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGAV | P06756 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | RIOK2 | Q9BVS4 | 4/20 | 0.33 |
| ▸ | GSK3A | P49840 | 3/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.33 |
| ▸ | MC5R | P33032 | 8/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.32 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650858 | 0.89 | ITGB3 (0.38) | TRPC3TRPC7TRPC5ITGB3ITGAV | |
| Hydrochloric Acid SCHEMBL8120478 | 0.88 | ITGB3 (0.38) | TRPC3TRPC7TRPC5ITGB3ITGAV | |
| SCHEMBL7750609 | 0.87 | ROCK1 (0.38) | TRPC3TRPC7TRPC5ITGB3ITGAV | |
| SCHEMBL8119519 | 0.84 | NPC1 (0.38) | — | |
| SCHEMBL7750605 | 0.81 | NPY1R (0.33) | ITGB3ITGAVITGA2B | |
| SCHEMBL7746039 | 0.80 | ITGB3 (0.33) | ITGB3ITGAVITGA2B | |
| SCHEMBL8126909 | 0.77 | CASP1 (0.43) | — | |
| SCHEMBL8113828 | 0.76 | REN (0.37) | ITGB3ITGAVITGA2B | |
| SCHEMBL7801972 | 0.76 | NPY1R (0.42) | MC3RMC4RITGB3ITGAVITGA2B | |
| SCHEMBL8111678 | 0.76 | ITGB3 (0.32) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |