Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL28200770 | 0.85 | APP (0.66) | APPKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL492221 | 0.85 | APP (0.70) | APPKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL20328415 | 0.85 | APP (0.70) | APPKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL20328414 | 0.85 | APP (0.70) | APPKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL7801278 | 0.85 | NFE2L2 (0.55) | APPKMT2AALDH1A1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL7787525 | 0.84 | NFE2L2 (0.53) | APPKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL31096483 | 0.83 | APP (0.68) | APPKMT2AALDH1A1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL15269629 | 0.83 | APP (0.68) | APPKMT2AALDH1A1LMNAPOLB | |
| Ethane SCHEMBL10589507 | 0.83 | APP (0.68) | APPKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL28853641 | 0.83 | APP (0.68) | APPKMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |