Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068142 | 0.93 | BRD4 (0.33) | BLM | |
| SCHEMBL11318608 | 0.93 | BRD4 (0.33) | BLM | |
| SCHEMBL5068820 | 0.93 | BRD4 (0.33) | BLM | |
| SCHEMBL29127 | 0.93 | BRD4 (0.33) | BLM | |
| SCHEMBL1067025 | 0.93 | BRD4 (0.33) | BLM | |
| SCHEMBL28167001 | 0.90 | BRD4 (0.32) | BLM | |
| Ethylene Glycol SCHEMBL28167207 | 0.87 | LMNA (0.33) | — | |
| SCHEMBL8906523 | 0.87 | — | — | |
| Fumaric Acid SCHEMBL8972811 | 0.87 | BLM (0.45) | BLMINMT | |
| Maleic Acid SCHEMBL6356254 | 0.87 | BLM (0.45) | BLMINMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904042-A4 | COSMETIC COMPOSITION FOR REJUVENATION OF SKIN WITHOUT SKIN IRRITATION | ISP INVESTMENTS INC (US) | 2001-08-22 | — | — | EP | claimed |
| CN-1218387-A | Cosmetic composition for rejuvenation of skin without skin irratation | ISP INVESTMENTS INC (US) | 1999-06-02 | — | — | CN | claimed |
| EP-0904042-A1 | COSMETIC COMPOSITION FOR REJUVENATION OF SKIN WITHOUT SKIN IRRITATION | ISP INVESTMENTS INC. (US) | 1999-03-31 | — | — | EP | claimed |
| WO-1997042929-A1 | COSMETIC COMPOSITION FOR REJUVENATION OF SKIN WITHOUT SKIN IRRITATION | ISP INVESTMENTS INC. (US) | 1997-11-20 | — | — | WO | claimed |