Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776611 | 0.78 | PPARG (0.64) | PPARGNFE2L2LMNATRPA1ALDH1A1 | |
| SCHEMBL13290905 | 0.78 | PPARG (0.64) | PPARGNFE2L2LMNATRPA1ALDH1A1 | |
| SCHEMBL28115705 | 0.77 | PPARG (0.62) | PPARGNFE2L2LMNAALDH1A1HTT | |
| SCHEMBL525688 | 0.73 | ALDH1A1 (0.43) | PPARGNFE2L2LMNATRPA1ALDH1A1 | |
| SCHEMBL8074310 | 0.73 | ALDH1A1 (0.39) | LMNAALDH1A1CYP2A6HTTKDM4E | |
| Styrene SCHEMBL16236539 | 0.71 | PPARG (0.55) | PPARGNFE2L2LMNAALDH1A1HTT | |
| SCHEMBL4780708 | 0.70 | PSIP1 (0.44) | PPARGNFE2L2LMNAALDH1A1CYP2A6 | |
| SCHEMBL5333467 | 0.70 | HSP90AA1 (0.41) | LMNAALDH1A1CYP2A6HTTKMT2A | |
| SCHEMBL28796892 | 0.69 | TRPA1 (0.53) | PPARGNFE2L2LMNATRPA1ALDH1A1 | |
| SCHEMBL971099 | 0.69 | CA2 (0.46) | LMNAALDH1A1CYP2A6MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983064-A4 | PYRROLES AS sPLA2 INHIBITORS | LILLY CO ELI (US) | 2001-01-31 | — | — | EP | disclosed |
| EP-0983064-A1 | PYRROLES AS sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998025609-A1 | PYRROLES AS sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |