Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 10/20 | 0.44 |
| ▸ | HTR1B | P28222 | 10/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8031070 | 0.99 | HTR1D (0.44) | HTR1DHTR1BSIGMAR1ROCK2CCR2 | |
| SCHEMBL7798179 | 0.81 | HTR1D (0.46) | HTR1DHTR1BHTR3EHTR3BHTR3A | |
| SCHEMBL7804121 | 0.81 | HTR1D (0.44) | HTR1DHTR1BSIGMAR1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL7805955 | 0.81 | HTR1D (0.38) | HTR1DHTR1BHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8172775 | 0.80 | HTR1D (0.45) | HTR1DHTR1BSIGMAR1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL8031546 | 0.80 | HTR1D (0.44) | HTR1DHTR1BSIGMAR1ROCK2ROCK1 | |
| SCHEMBL7798296 | 0.80 | HTR7 (0.40) | HTR1DHTR1BHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8162484 | 0.79 | HTR7 (0.40) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7804089 | 0.79 | HTR7 (0.44) | SIGMAR1ALDH1A1 | |
| SCHEMBL7804162 | 0.77 | HTR1D (0.45) | HTR1DHTR1BSIGMAR1ROCK2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |