Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 7/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795443 | 1.00 | CXCR2 (0.41) | CXCR2CXCR1MEN1KMT2ACCR6 | |
| SCHEMBL7801221 | 0.89 | CXCR2 (0.41) | CXCR2CXCR1CCR6CXCL8CYP3A4 | |
| Hydrochloric Acid SCHEMBL7801287 | 0.88 | CXCR2 (0.41) | CXCR2CXCR1CCR6CXCL8CYP3A4 | |
| SCHEMBL7801220 | 0.86 | LMNA (0.38) | CXCR2CXCR1MEN1KMT2ACCR6 | |
| Hydrochloric Acid SCHEMBL7802250 | 0.86 | LMNA (0.37) | CXCR2CXCR1MEN1KMT2ACCR6 | |
| Hydrochloric Acid SCHEMBL7804207 | 0.85 | CCR6 (0.36) | CXCR2CXCR1MEN1KMT2ACCR6 | |
| SCHEMBL7787711 | 0.81 | CXCR2 (0.41) | CXCR2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL7787459 | 0.81 | CXCR2 (0.41) | CXCR2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL7801434 | 0.81 | CXCR2 (0.40) | CXCR2CXCR1CCR6LMNAGPR139 | |
| SCHEMBL7805393 | 0.81 | CXCR2 (0.40) | CXCR2CXCR1MEN1KMT2ACCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |