Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7802250 | 0.99 | LMNA (0.37) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL7803619 | 0.90 | MAOA (0.37) | LMNAMEN1KMT2ACCR6GRIN2D | |
| Hydrochloric Acid SCHEMBL7805326 | 0.89 | MAOA (0.39) | LMNAMEN1KMT2ACCR6GRIN2D | |
| SCHEMBL7804119 | 0.86 | CXCR2 (0.41) | LMNAMEN1MAPTKMT2ACCR6 | |
| SCHEMBL7795443 | 0.86 | CXCR2 (0.41) | LMNAMEN1MAPTKMT2ACCR6 | |
| SCHEMBL7780580 | 0.85 | RCE1 (0.40) | LMNAMEN1MAPTHTTKMT2A | |
| Hydrochloric Acid SCHEMBL7785319 | 0.85 | RCE1 (0.41) | LMNAMEN1MAPTHTTKMT2A | |
| Hydrochloric Acid SCHEMBL7804207 | 0.82 | CCR6 (0.36) | MEN1KMT2ACCR6CXCL8CXCR2 | |
| SCHEMBL7789338 | 0.78 | RCE1 (0.45) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7780764 | 0.77 | RCE1 (0.47) | MEN1KMT2AGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |