Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR1F | P30939 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SCD | O00767 | 6/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358945 | 0.89 | ALOX15 (0.52) | HTR1BHTR1AHTR1FALOX15GAA | |
| SCHEMBL3369338 | 0.88 | PIK3CD (0.43) | HTR1BHTR1AHTR1FSCDPIK3CD | |
| SCHEMBL3354280 | 0.85 | DRD2 (0.42) | HTR1BHTR1AHTR1FALOX15SCD | |
| SCHEMBL30778591 | 0.85 | KDM4E (0.43) | HTR1BHTR1AHTR1FSCDPIK3CD | |
| SCHEMBL3352822 | 0.85 | HTR1A (0.41) | HTR1BHTR1AHTR1FALOX15SCD | |
| SCHEMBL3351511 | 0.85 | HTR1A (0.41) | HTR1BHTR1AHTR1FALOX15GAA | |
| SCHEMBL15830330 | 0.84 | HTR1A (0.55) | HTR1BHTR1AHTR1FALOX15GAA | |
| SCHEMBL3351612 | 0.83 | OGFRL1 (0.40) | HTR1BHTR1AHTR1FSCDPIK3CD | |
| SCHEMBL31758051 | 0.83 | HTR1A (0.54) | HTR1BHTR1AHTR1FALOX15GAA | |
| SCHEMBL1863636 | 0.81 | HTR1A (0.45) | HTR1BHTR1AHTR1FSCDPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |