Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496805 | 1.00 | ADRB2 (0.59) | ADRB2ADRB1SMN1; SMN2TSHRTP53 | |
| SCHEMBL9123406 | 0.91 | ADRB2 (0.62) | ADRB2ADRB1SMN1; SMN2TSHRTP53 | |
| SCHEMBL10922740 | 0.85 | ADRB2 (0.71) | ADRB2ADRB1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL1496742 | 0.84 | ADRB2 (0.66) | ADRB2ADRB1SMN1; SMN2TSHRTP53 | |
| SCHEMBL1496573 | 0.82 | LMNA (0.56) | ADRB2ADRB1TSHRLMNAKMT2A | |
| SCHEMBL7804281 | 0.82 | LMNA (0.56) | ADRB2ADRB1TSHRLMNAKMT2A | |
| SCHEMBL12565554 | 0.82 | ALOX5 (0.47) | ADRB2ADRB1SMN1; SMN2TSHRTP53 | |
| SCHEMBL13881546 | 0.81 | HIF1A (0.51) | SMN1; SMN2TSHRTP53LMNAL3MBTL1 | |
| SCHEMBL14896741 | 0.81 | TSHR (0.71) | ADRB2ADRB1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL16002431 | 0.81 | TSHR (0.71) | ADRB2ADRB1SMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104395-A1 | STEREOSELECTIVE RING OPENING REACTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009463-A1 | STEREOSELECTIVE RING OPENING REACTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-02-24 | — | — | WO | disclosed |