Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408548 | 0.88 | TOP2A (0.53) | MAOALMNAMAPTHPGDMAPK1 | |
| SCHEMBL6409081 | 0.88 | HKDC1 (0.46) | MAOALMNAMAPTHPGDMAPK1 | |
| SCHEMBL7811209 | 0.81 | MAOA (0.53) | MAOAKMT2AALDH1A1 | |
| SCHEMBL6408521 | 0.79 | LMNA (0.42) | MAOALMNAMAPTHPGDMAPK1 | |
| SCHEMBL6407769 | 0.79 | LMNA (0.44) | MAOALMNAMAPTHPGDMAPK1 | |
| SCHEMBL6407142 | 0.79 | MAPT (0.46) | MAOALMNAMAPTHPGDMAPK1 | |
| SCHEMBL6409043 | 0.79 | MAPT (0.46) | MAOALMNAMAPTHPGDMAPK1 | |
| SCHEMBL7811692 | 0.78 | MAOA (0.53) | MAOAKMT2AALDH1A1 | |
| SCHEMBL7804497 | 0.78 | MAOA (0.53) | MAOAKMT2AALDH1A1 | |
| SCHEMBL7813560 | 0.78 | MAOA (0.53) | MAOAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588796-B1 | SAMPANGINE DERIVATIVES USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | UNIV MISSISSIPPI (US) | 2001-04-04 | — | — | EP | disclosed |
| US-5530004-A | ADMINISTERING SAMPANGINE AND CLEISTOPHOLINE ANALOGS | THE UNIVERSITY OF MISSISSIPPI (US) | 1996-06-25 | — | — | US | disclosed |
| EP-0588796-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1994-03-30 | — | — | EP | disclosed |
| US-5227383-A | Sampangine analogs | THE UNIVERSITY OF MISSISSIPPI (US) | 1993-07-13 | — | — | US | disclosed |
| WO-1992022297-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1992-12-23 | — | — | WO | disclosed |