Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811458 | 0.91 | GAA (0.47) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL7817532 | 0.89 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL7813666 | 0.84 | PPARG (0.52) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL7814214 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL7804398 | 0.81 | PPARG (0.49) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL7810037 | 0.80 | PPARG (0.50) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL7804335 | 0.79 | TSHR (0.67) | ALDH1A1SMN1; SMN2PPARGMAPTTSHR | |
| SCHEMBL7811577 | 0.79 | PPARG (0.49) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL7811630 | 0.79 | PPARA (0.60) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL7811760 | 0.79 | PPARG (0.49) | ALDH1A1SMN1; SMN2PPARGPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |