Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804380 | 0.92 | KCNA5 (0.52) | KMT2ANPC1L3MBTL1L3MBTL3HPGD | |
| SCHEMBL7804403 | 0.85 | DRD4 (0.56) | KMT2ANPC1L3MBTL1L3MBTL3HPGD | |
| SCHEMBL7804419 | 0.79 | NPC1 (0.51) | KMT2ANPC1HPGDKCNA5ALDH1A1 | |
| SCHEMBL23268667 | 0.78 | ACHE (0.55) | KMT2AL3MBTL1L3MBTL3HPGDALDH1A1 | |
| SCHEMBL7804443 | 0.78 | MEN1 (0.52) | KMT2AHTTALDH1A1LMNATP53 | |
| SCHEMBL7813958 | 0.77 | MME (0.47) | KMT2ANPC1HPGDKCNA5CYP3A4 | |
| SCHEMBL7811501 | 0.77 | KMT2A (0.47) | KMT2ANPC1L3MBTL1L3MBTL3HPGD | |
| SCHEMBL10871010 | 0.75 | ACHE (0.60) | KMT2AL3MBTL1L3MBTL3HPGDALDH1A1 | |
| SCHEMBL7804396 | 0.75 | NPC1 (0.54) | KMT2ANPC1HPGDKCNA5LMNA | |
| SCHEMBL7811215 | 0.73 | NPC1 (0.42) | KMT2ANPC1L3MBTL1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |