Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FASN | P49327 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | MAPK7 | Q13164 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810206 | 0.91 | HSD11B1 (0.54) | HSD11B1GAALMNAALDH1A1HPGD | |
| SCHEMBL7810069 | 0.91 | HSD11B1 (0.59) | HSD11B1LMNAALDH1A1HPGDHIF1A | |
| SCHEMBL7811341 | 0.90 | PARP10 (0.64) | HSD11B1GAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7814102 | 0.90 | HSD11B1 (0.53) | HSD11B1GAAPOLBLMNAALDH1A1 | |
| SCHEMBL7813621 | 0.90 | HSD11B1 (0.53) | HSD11B1GAAPOLBLMNAALDH1A1 | |
| SCHEMBL7817468 | 0.90 | PPARA (0.57) | HSD11B1LMNAALDH1A1SMN1; SMN2FASN | |
| SCHEMBL7814130 | 0.88 | LMNA (0.54) | HSD11B1GAALMNAALDH1A1PARP10 | |
| SCHEMBL7814025 | 0.88 | HSD11B1 (0.63) | HSD11B1GAAPOLBLMNAALDH1A1 | |
| SCHEMBL7810110 | 0.88 | HSD11B1 (0.51) | HSD11B1GAAHPGDPARP10MGLL | |
| SCHEMBL7817531 | 0.83 | HSD11B1 (0.46) | HSD11B1GAALMNAFASNPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |