Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810069 | 0.91 | HSD11B1 (0.59) | LMNAHSD11B1PARP10CYP2C9TSHR | |
| SCHEMBL7810206 | 0.88 | HSD11B1 (0.54) | LMNAHSD11B1PARP10CYP2C9TSHR | |
| SCHEMBL7804429 | 0.88 | HSD11B1 (0.66) | LMNAHSD11B1PARP10GAAALDH1A1 | |
| SCHEMBL7810099 | 0.88 | ALDH1A1 (0.52) | LMNAHSD11B1EPHX2GAAALDH1A1 | |
| SCHEMBL7810110 | 0.88 | HSD11B1 (0.51) | HSD11B1PARP10TSHRPPARAGAA | |
| SCHEMBL7814102 | 0.87 | HSD11B1 (0.53) | LMNAHSD11B1PARP10CYP2C9TSHR | |
| SCHEMBL7817468 | 0.87 | PPARA (0.57) | LMNAHSD11B1PARP10CYP2C9TSHR | |
| SCHEMBL7813621 | 0.87 | HSD11B1 (0.53) | LMNAHSD11B1PARP10CYP2C9TSHR | |
| SCHEMBL7811341 | 0.87 | PARP10 (0.64) | LMNAHSD11B1KDM4EPARP10CYP2C9 | |
| SCHEMBL7817510 | 0.87 | BCL9 (0.57) | LMNAHSD11B1KDM4ERECQLPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |