Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.64 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810206 | 0.90 | HSD11B1 (0.54) | PARP10HSD11B1PARP14ALDH1A1LMNA | |
| SCHEMBL7804429 | 0.90 | HSD11B1 (0.66) | PARP10HSD11B1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7810069 | 0.90 | HSD11B1 (0.59) | PARP10HSD11B1NPC1RAB9AATM | |
| SCHEMBL7810110 | 0.89 | HSD11B1 (0.51) | PARP10HSD11B1MEN1KMT2AGAA | |
| SCHEMBL7813621 | 0.89 | HSD11B1 (0.53) | PARP10HSD11B1PARP14ALDH1A1LMNA | |
| SCHEMBL7814102 | 0.89 | HSD11B1 (0.53) | PARP10HSD11B1PARP14ALDH1A1LMNA | |
| SCHEMBL7817468 | 0.89 | PPARA (0.57) | PARP10HSD11B1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7814130 | 0.87 | LMNA (0.54) | PARP10HSD11B1ALDH1A1LMNAKDM4E | |
| SCHEMBL7814100 | 0.87 | BCL9 (0.56) | PARP10HSD11B1NPC1RAB9AATM | |
| SCHEMBL7804251 | 0.85 | CPS1 (0.47) | PARP10PARP14ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |