Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805751 | 0.95 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL7799321 | 0.95 | DPP8 (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL7806688 | 0.92 | TDP1 (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL7799332 | 0.86 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL7804672 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL7805781 | 0.81 | DPP8 (0.38) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL9020070 | 0.81 | CCR5 (0.43) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL9020352 | 0.80 | CCR5 (0.42) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL10698245 | 0.80 | TDP1 (0.42) | ALDH1A1MAPTDPP8DPP9TDP1 | |
| SCHEMBL5723978 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773222-B1 | CARBAPENEM DERIVATIVE | EISAI CO LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6037341-A | HAVING POTENT ANTIMICROBIAL EFFECTS OVER GRAM-POSITIVE BACTERIA AND GRAM-NEGATIVE BACTERIA | EISAI CO., LTD. (JP) | 2000-03-14 | — | — | US | disclosed |
| EP-0773222-A1 | NOVEL CARBAPENEM DERIVATIVE | Eisai Co., Ltd. (JP) | 1997-05-14 | — | — | EP | disclosed |