SCHEMBL26049385

SCHEMBL26049385

CC(CCOCCC(=O)O)N(CCOCCC(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.30
CHRNB2 P17787 2/20 0.30
CHRNA4 P43681 2/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25851225 0.90
SCHEMBL25835897 0.77 CA14 (0.41) L3MBTL1BLMPMP22HSD17B10HDAC1
SCHEMBL24340623 0.76 CA14 (0.40) L3MBTL1BLMPMP22HSD17B10HDAC1
SCHEMBL18281954 0.75 CTSS (0.34) L3MBTL1HDAC1HDAC2HDAC6
SCHEMBL26689402 0.75 BLM (0.38) L3MBTL1BLMPMP22HSD17B10HDAC1
SCHEMBL946261 0.75 BLM (0.38) L3MBTL1BLMPMP22HSD17B10HDAC1
SCHEMBL18285697 0.74 CA14 (0.37) L3MBTL1HDAC1HDAC2HDAC6
SCHEMBL23564375 0.74 CTSL (0.37) HDAC1HDAC2HDAC6
SCHEMBL13567944 0.73 CA14 (0.34) L3MBTL1CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL30104830 0.72 HDAC6 (0.32) HDAC1HDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 L3MBTL1 569/4885CHRNB2 251/4885CHRNA4 483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.