Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KLK1 | P06870 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14886582 | 0.81 | TSHR (1.00) | TSHRNOTUMS1PR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21332768 | 0.78 | ALDH1A1 (0.77) | TSHRNOTUMS1PR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21333495 | 0.77 | NOTUM (0.73) | TSHRNOTUMS1PR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8304416 | 0.76 | NOTUM (1.00) | TSHRNOTUMS1PR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7803535 | 0.76 | MAPT (0.58) | TSHRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL8940579 | 0.73 | TSHR (0.80) | TSHRNOTUMSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11163046 | 0.72 | ERCC5 (0.51) | TSHRSMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL18038971 | 0.72 | NOTUM (0.64) | TSHRNOTUMS1PR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2036338 | 0.72 | KMT2A (0.54) | SMN1; SMN2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL17385567 | 0.71 | SMN1; SMN2 (1.00) | TSHRNOTUMS1PR2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953875-B1 | Photographic element containing yellow coupler | EASTMAN KODAK CO (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0953874-B1 | Photographic element comprising yellow dye-forming photographic coupler | EASTMAN KODAK CO (US) | 2001-08-16 | — | — | EP | disclosed |
| US-6057087-A | Photographic element containing yellow coupler | EASTMAN KODAK COMPANY (US) | 2000-05-02 | — | — | US | disclosed |
| US-6015658-A | ELEMENT CONTAINING SILVER HALIDE EMULSION LAYER HAVING ASSOCIATED THEREWITH DYE FORMING COUPLER BASED ON MULTIPLY SUBSTITUTED PYRROLOYLACYLACETAMIDO COMPOUND | EASTMAN KODAK COMPANY (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0953875-A1 | Photographic element containing yellow coupler | EASTMAN KODAK COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0953874-A1 | Photographic element comprising yellow dye-forming photographic coupler | EASTMAN KODAK COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |